Rich G. PMID:23381626 Carter of Oregon State University described (J. Am. Chem. Soc. 2008, 130, 9238 DOI: 10.1021/ja803613w) the first enantioselective synthesis of the Lycopodium alkaloid (-)-lyopodine (3). A key…
The tetracyclic alkaloids Nankakurine A and Nankakurine B were isolated from the club moss Lycopodium hamiltonii. A preliminary study of the biological activity of Nankakurine A suggested that it could…
The Zoanthus alkaloids, exemplified by (-)-norzoanthamine (3a) and zoanthamine (3b), show promising activity against osteoporosis. PMID:24189672 Susumu Kobayashi of the Tokyo University of Science assembled (Angew. Chem. Int. Ed. 2009,…
(+)-Pinnatoxin A (3), isolated from the shellfish Pinna muricata, is thought to be a calcium channel activator. A key transformation in the synthesis of 3 reported (J. Am. Chem. Soc.…
N and theCharacterization of your mAbThe cross reactivity in the mAb 2G12E1 was tested using artesunate, dihydroartemisinin, artemisinin along with other important antimalarial drugs in icELISA (Table 1). The cross…
Ug/ml. Following selection, steady clones have been isolated by limiting dilution. Knockdown was monitored by operating complete cell lysates and/or spent media on gels and probing with versican antibodies as…
The compact sesquiterpene (+)-fomannosin (3), isolated from the pathogenic fungus Fomes annonsus, presents an interesting set of challenges for the organic synthesis chemist, ranging from the strained cyclobutene to the…
The zaragozic acids, exemplified by Zaragozic Acid C (3), are picomolar inhibitors of cholesterol biosynthesis. Jeffrey S. PMID:26446225 2126818-91-3 custom synthesis Johnson of the University of North Carolina developed (J.…
Several noteworthy new developments in the protection and deprotection of alcohols have been reported. Price of 2-Aminoacetamide Andrea Biffis of the Università di Padova has developed (Adv. Synth. Catal. 2007,…
A recent publication by Mats Larhed and co-workers from Uppsala University (J. Org. 5-Chloro-4-methylpyridin-3-amine Purity Chem. 2004, 69, 5212.DOI: 10.1021/jo049434t)describes dioxygen-promoted regioselective oxidativeHeck arylations of electron-rich olefins with arylboronic acids.…
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