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Substituted Benzenes: The Saikawa/Nakata Synthesis of Kendomycin

Chemexpress June 1, 2024 0 Comments

Jianbo Wang of Peking University described (Angew. Chem. Int. Ed. 2010, 49, 2028. DOI: 10.1002/anie.200906699) the Au-promoted bromination of a benzene derivative such as 1 with N-bromosuccinimide. In a one-pot…

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Advances in Alkene Metathesis: The Hoveyda Synthesis of (+)-Quebrachamine

Chemexpress June 1, 2024 0 Comments

There are two major impediments to the scaling up of alkene metathesis, reducing the amount of the expensive Ru catalyst required, and minimizing residual Ru in the product. Robert H.…

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Alkaloid Synthesis: (S)-Nicotine (Helmchen), (+)-CP-99,994 (Shi),

Chemexpress June 1, 2024 0 Comments

(-)-Adaline (Yu), (-)-Securinine (Bayón/Figueredo), Alkaloid 223A (Aubé), (-)-Huperzine A (Fukuyama) The recent development of practical methods for the asymmetric preparation of amines has enabled creative approaches to alkaloid construction. Cyclopropylmethyl…

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Strictly consecutive and SA-regulated manner around the SA sensor protein NPR

Chemexpress May 31, 2024 0 Comments

Strictly consecutive and SA-regulated manner on the SA sensor protein NPR1, enabling NPR1 to monitor progressing threat by pathogens and to market appropriate defense gene activation at distinct stages of…

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D on a typical haplotype, probably from a popular AJ founder.

Chemexpress May 31, 2024 0 Comments

D on a frequent haplotype, probably from a frequent AJ founder. Notably, the variant is just not observed inside the publically readily available information on approximately 9,000 folks (ESP 6500…

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Metal-Mediated Carbocyclic Construction: The Kobayashi Synthesis of (+)-Fomitellic Acid B

Chemexpress May 31, 2024 0 Comments

Jin K. Cha of Wayne State University described (J. Org. Chem. 2009, 74, 5528. DOI: 10.1021/jo900823h) the diastereoselective intramolecular cyclopropanation of nitriles with homoallylic alcohols such as 1. Valery V.…

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Functional Group Protection

Chemexpress May 31, 2024 0 Comments

Bekington Myrboh of North-Eastern Hill University reported (Tetrahedron Lett. 2010, 51, 2862. DOI: 10.1016/j.tetlet.2010.03.084) a convenient procedure for the oxidative removal of a 1,3-oxathiolane 1 or a 1,3-dithiolane. Sang-Gyeong Lee…

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"Organometallic" Coupling without the Metal!

Chemexpress May 31, 2024 0 Comments

Ususally, an aryl halide such as 1 will be coupled with the arylboronic acid 2 using a Pd catalyst. Nicholas Leadbeater of King’s College, London, reports (J. Org. BuyTri(1-adamantyl)phosphine Chem.…

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Best Synthetic Methods: Oxidation

Chemexpress May 31, 2024 0 Comments

Karl A. 6-Bromo-7-fluoroisobenzofuran-1(3H)-one uses Scheidt of Northwestern University described(Org. Lett. PMID:34645436 2009, 11, 1651.DOI: 10.1021/ol900306v)the oxidation of primary alcohols such as 1 in the presence of an indole 2. The…

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Enantioselective Construction of Alkylated Centers: The Maier Synthesis of Platencin

Chemexpress May 31, 2024 0 Comments

Jaesook Yun of Sungkyunkwan University devised(J. Org. Price of Acid-PEG3-C2-Boc Chem. 2009, 74, 4232.DOI: 10.1021/jo900530s)a method, based on conjugate addition to a cyano alkyne, for the preparation of nitriles such…

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2-amino-N-cyclopentylpropanamide hydrochloride (CAS 1214638-91-1)

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2-Aminoanthracene (CAS 613-13-8)

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2-amino-N-(4-fluorobenzyl)ethanesulfonamide hydrochloride

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2-Amino-6-ethoxybenzothiazole (CAS 94-45-1)

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