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C-H Functionalization: The Chen Synthesis of Celogentin C

Chemexpress June 12, 2024 0 Comments

Christian R. Buy27194-74-7 Goldsmith of Auburn University developed (Synlett 2010, 1377. DOI: 10.1055/s-0029-1219832) a method for radical chlorination of 1, using commercial peracetic acid. PMID:23613863 Noritaka Mizuno of the University…

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Ven the reduced Rad51 function by the Srs2 overexpression, the interhomolog

Chemexpress June 11, 2024 0 Comments

Ven the lowered Rad51 function by the Srs2 overexpression, the interhomolog recombination is channeled in to the intersister recombination, resulting in lowered recombination. The reduced Rad51 assembly within the mutant…

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Ed in Amaryllidaceae alkaloids synthesis had been identified for the first time

Chemexpress June 11, 2024 0 Comments

Ed in Amaryllidaceae alkaloids synthesis have been identified for the very first time and are worthyFigure 6. Distribution of putative single nucleotide polymorphisms (SNP) in the transcriptome of L. aurea.…

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New Methods for C-C Bond Construction

Chemexpress June 11, 2024 0 Comments

Luigino Troisi of the University of Salento found (Tetrahedron Lett. 2010, 51, 371. DOI: 10.1016/j.tetlet.2009.11.023) that a variety of primary and secondary amines could be coupled with a benzylic halide…

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Total Synthesis of the Galbulimima Alkaloid GB 13

Chemexpress June 11, 2024 0 Comments

Lew Mander of the Australian National University recently reported (J. Am. Chem. PMID:33679749 Soc. 2003, 125, 2400.DOI: 10.1021/ja029725o)the total synthesis of the pentacyclic alkaloid GB 133, which had been isolated…

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Heteroaromatic Construction: The Fukuyama Synthesis of Tryprostatin A

Chemexpress June 11, 2024 0 Comments

Alessandro Palmieri of the University of Camerino developed (Synlett 2010, 2468. DOI: 10.1055/s-0030-1258031) the condensation of a nitro acrylate 1 with a 1,3-dicarbonyl partner 2 to give the furan 3.…

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Functionalization and Homologation of Alkenes

Chemexpress June 11, 2024 0 Comments

Masahito Ochiai developed ( 2008, March 24) the iodosobenzene-mediated cleavage of alkenes to keto aldehydes. PMID:23557924 Thottumkara K. Vinod of Western Illinois University described (Org. Lett. 2010, 12, 5640. DOI:…

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Metal Mediated C-C Ring Construction: The Nevado Route to (-)- Frondosin A

Chemexpress June 11, 2024 0 Comments

Barry M. 6-Bromo-3-chloroisoquinoline structure Trost of Stanford University generated (J. Am. Chem. Soc. 2011, 133, 4766. DOI: 10.1021/ja200971v) a β-keto carbene from the propargyl alcohol 1, leading to the cyclopropane…

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Enantioselective Preparation of Alkylated Stereogenic Centers

Chemexpress June 11, 2024 0 Comments

Jon D. Stewart of the University of Florida established (Chem. Commun. 2010, 46, 8558. DOI: 10.1039/C0CC03119D) a scalable enzymatic reduction of geranial 1 to citronellal 2. Andreas S. Bommarius of…

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C-O Ring Construction: (-)-Sclerophytin A (Morken), (+)-Dictyosphaeric Acid

Chemexpress June 11, 2024 0 Comments

(Taylor), Goniothalesdiol A (Xie/She), (-)-7-Deoxyloganin (Lupton), (-)-Apicularen A (Uenishi)L-783, 277 (Banwell) In the course of a synthesis of (-)-Sclerophytin A (3), James P. Morken of Boston College showed (J. Am.…

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