C-O Ring Construction: The Ito Synthesis of Callilongisin B
Chemexpress Young Ho Rhee of the Pohang University of Science and Technology assembled the dihydrofuran 3 by Pd-mediated coupling of the allene 1 with the keto acid 2, followed by ring-closing…
Metal-Mediated C-C Ring Construction: The Chen/Zhang Synthesis of PGF2α
Ilan Marek of Technion – Israel Institute of Science and Technology demonstrated that the homoallylic ether of the cyclopropene 1 was sufficient to direct the regioselectivity of the addition of…
The Jia Synthesis of Euphorikanin A
Euphorikanin A (3), isolated from the roots of the Chinese medicinal herb Euphorbia kansui, showed the ability to reactivate latent HIV. En route to 3, Yanxing Jia of Peking University…
The Zhang Synthesis of Talassamine
The structure of talassamine (3), isolated from the epigeal part of Aconitum talassicum (Ranunculaceae), a perennial herb of Tibet and western China, was established by x-ray analysis. En route to…
Cyclocondensation of Hydrazine Derivatives with Alkyl Dihalides or Ditosylates
Rajender S. Varma and Yuhong Ju from the U.S. Environmental Protection Agency have reported (Tetrahedron Lett. 5-Bromo-1H-pyrrole-2-carboxylic acid In stock 2005, 46, 6011. DOI: 10.1016/j.tetlet.2005.07.018)on the direct syntheses of 4,5-dihydro-pyrazole,pyrazolidine…
TeCoA ligase (EC six.2.1.9), share exactly the same evolutionary origin. Due to the fact SucCD from
TeCoA ligase (EC six.two.1.9), share precisely the same evolutionary origin. Because SucCD from M. extorquens AM1 is just not in a position to compensate for the MtkAB deficiency in the…
L author and source are credited. n Corresponding author. Tel.: 1 215 898 8819; fax
L author and source are credited. n Corresponding author. Tel.: 1 215 898 8819; fax: 1 215 573 6810. Email address: [email protected] (N.G. Avadhani). 1 Present address: The USFood and…
The Gao Synthesis of Perovskatone D and Perovskone
Perovskone (4), isolated from Perovskia abratanoides, contains a complex heptacyclic framework and eight adjacent stereogenic centers. En route to 4 and other Salvia triterpenoids, Shuanhu Gao of East China Normal…
The Dai Synthesis of Hamigeran M
Of the several hamigerans isolated from the marine sponge Hamigera tarangaensis, only two contain nitrogen. Mingji Dai of Purdue University devised a route to one of those, hamigeran M (3),…
The Herzon Synthesis of Euonyminol
Euonyminol (3) was isolated from the thunder duke vine, Tripterygium wilfordii, used in traditional Chinese medicine. In the course of a synthesis of 3, Seth B. Herzon of Yale University…