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C-H Functionalization: The Harusawa Synthesis of Trichodenone C

Chemexpress March 14, 2024 0 Comments

Lutz Ackermann of the Georg-August-Universität Göttingen effected azidation of 1 selectively at the methine distal to the electron-withdrawing ester, leading to 2 (Chem. Sci. 2021, 12, 2890. DOI: 10.1039/D0SC05924B). Li-Zhu…

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Functional Group Protection: The Reisman Synthesis of Perseanol

Chemexpress March 14, 2024 0 Comments

Jan Streuff of the Albert-Ludwigs-Universität Freiburg developed conditions to remove the alkene-containing alkyl group from 1, leading to 2 (ACS Catal. 2020, 10, 6409. DOI: 10.1021/acscatal.0c01605). Dayong Sang and Juan…

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Arrays of Stereogenic Centers: The Scheidt Synthesis of Rauwolscine

Chemexpress March 14, 2024 0 Comments

David R. Williams of Indiana University showed that the enantioselective Katsuki epoxidation of 1 delivered 2 (Org. Lett. 2020, 22, 4118. DOI: 10.1021/acs.orglett.0c01177). Harunobu Mitsunama and Motomu Kanai of the…

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Pectrum is observed, the imply residue ellipticity at 220 nm can be

Chemexpress March 13, 2024 0 Comments

Pectrum is noticed, the mean residue ellipticity at 220 nm is often followed with growing temperature to measure thermal stability. Enzyme digestion and/or CD studies have been performed for the…

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Kine receptor 9 (CCR9)chemokine ligand 25 (CCL25) axis. J. Biol. Chem. 2010, 285, 234963505. 47. Fuchs

Chemexpress March 13, 2024 0 Comments

Kine receptor 9 (CCR9)chemokine ligand 25 (CCL25) axis. J. Biol. Chem. 2010, 285, 234963505. 47. Fuchs, B.; Schiller, J.; Wagner, U.; Hantzschel, H.; Arnold, K. The phosphatidylcholine/lysophosphatidylcholine ratio in human…

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Heteroaromatics: The Cho Synthesis of Tubifolidine

Chemexpress March 13, 2024 0 Comments

Antonio J. Moreno-Vargas of the Universidad de Sevilla drove the retro Diels-Alder disassembly of the 7-oxanorbornadiene 1 by reacting it selectively with benzyl azide, leading to the furan 2 (J.…

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Reduction: The Zhai Synthesis of Conidiogenone

Chemexpress March 13, 2024 0 Comments

Julian G. West of Rice University observed high diastereoselectivity in the reduction of the cyclic alkene 1 to 2 (J. Am. Chem. Soc. 2020, 142, 19316. DOI: 10.1021/jacs.0c09544). Christopher J.…

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Diels-Alder Cycloaddition: Lepadin F (Chen), Lammelodysidine A (Molga/ Mlynarski/Grzybowski/Mrksich), Cannogenol (Nakazaki),

Chemexpress March 13, 2024 0 Comments

cis-crotonin (Cai), Salvinorin A (Metz), Cephanolide A (Sarpong) Lepadin F (4), isolated from the tunicate Didemnum sp, showed antiplasmodial and antitrypanosomal activity. Xiaochuan Chen of Sichuan University prepared the precursor…

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Alkylated Sterogenic Centers: The Nagamitsu Synthesis of Habiterpenol

Chemexpress March 13, 2024 0 Comments

Chihui An and Megan H. Shaw of Merck Process achieved high ee in the reduction of the α-methylene acid 1 to the α-methyl acid 2 (Org. Lett. 2020, 22, 8320.…

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Cobalt Carbonyl-Mediated Synthesis of Ureas

Chemexpress March 13, 2024 0 Comments

Mats Larhed and co-workers from Uppsala University (Tetrahedron Lett. 5-Hydroxymethylfurfural Chemscene 2005, 46, 3335. DOI: 10.1016/j.tetlet.2005.03.076)have reported on a novel and very fast gas-free carbonylation method for the preparation of…

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