Substituted Benzenes: The Zhai Synthesis of Cephanolide B
Chemexpress Shangda Li and Gang Li of the Fujian Institute of Research on the Structure of Matter used the iodo nitro aromatic 2 to selectively iodinate the anilide 1, leading to…
C-O Ring Construction: The Makabe Synthesis of Muconin
Yu-Fei Ao and Hui Chen of the Institute of Chemistry, Chinese Academy of Sciences devised a mutant amidase that hydrolyzed the prochiral dihydrofuran bis amide 1 to the monoacid 2…
C-O Ring Construction: The Ito Synthesis of Callilongisin B
Young Ho Rhee of the Pohang University of Science and Technology assembled the dihydrofuran 3 by Pd-mediated coupling of the allene 1 with the keto acid 2, followed by ring-closing…
Metal-Mediated C-C Ring Construction: The Chen/Zhang Synthesis of PGF2α
Ilan Marek of Technion – Israel Institute of Science and Technology demonstrated that the homoallylic ether of the cyclopropene 1 was sufficient to direct the regioselectivity of the addition of…
The Jia Synthesis of Euphorikanin A
Euphorikanin A (3), isolated from the roots of the Chinese medicinal herb Euphorbia kansui, showed the ability to reactivate latent HIV. En route to 3, Yanxing Jia of Peking University…
The Zhang Synthesis of Talassamine
The structure of talassamine (3), isolated from the epigeal part of Aconitum talassicum (Ranunculaceae), a perennial herb of Tibet and western China, was established by x-ray analysis. En route to…
Cyclocondensation of Hydrazine Derivatives with Alkyl Dihalides or Ditosylates
Rajender S. Varma and Yuhong Ju from the U.S. Environmental Protection Agency have reported (Tetrahedron Lett. 5-Bromo-1H-pyrrole-2-carboxylic acid In stock 2005, 46, 6011. DOI: 10.1016/j.tetlet.2005.07.018)on the direct syntheses of 4,5-dihydro-pyrazole,pyrazolidine…
TeCoA ligase (EC six.2.1.9), share exactly the same evolutionary origin. Due to the fact SucCD from
TeCoA ligase (EC six.two.1.9), share precisely the same evolutionary origin. Because SucCD from M. extorquens AM1 is just not in a position to compensate for the MtkAB deficiency in the…
L author and source are credited. n Corresponding author. Tel.: 1 215 898 8819; fax
L author and source are credited. n Corresponding author. Tel.: 1 215 898 8819; fax: 1 215 573 6810. Email address: [email protected] (N.G. Avadhani). 1 Present address: The USFood and…
The Gao Synthesis of Perovskatone D and Perovskone
Perovskone (4), isolated from Perovskia abratanoides, contains a complex heptacyclic framework and eight adjacent stereogenic centers. En route to 4 and other Salvia triterpenoids, Shuanhu Gao of East China Normal…