Yujiro Hayashi of Tokyo University of Science and Teruaki Mukaiyama of the Kitasato Institute developed (Chem. Lett. 1220039-63-3 Chemical name 2008, 37, 592 DOI: 10.1246/cl.2008.592) a reduction-oxidation method for converting…
As new drug entities must be usually be prepared as single enantiomers, and as many contain one or more heterocyclic or carbocyclic rings, there is an increased emphasis on the…
Unsaturated half acid esters such as 1 are readily prepared by Stobbe condensation between dialkyl succinate and an aldehyde. Johannes G. de Vries of DSM and Floris P. 1,1-Diethoxy-3-phenylpropan-2-one web…
Dactylolide (Jennings), Cytotrienin A (Hayashi), Lepadin B (Charette), Blumiolide C (Altmann) To assemble the framework of the cytotoxic macrolide Amphidinolide X (3), Fèlix Urpí and Jaume Vilarrasa of the Universitat…
(+)-6′-Hydroxyarenarol (Anderson) V. T. Perchyonok and Kellie L. Tuck of Monash University found (Tetrahedron Lett. 2008, 49, 4777. DOI: 10.1016/j.tetlet.2008.05.097 ) that a concentrated solution of Bu4NCl and H3PO2 in…
F X. Peter Zhang of the University of South Florida extended (Org. PMID:24507727 Lett. 2009, 11, 2273. DOI: 10.1021/ol9005882) Co-catalyzed asymmetric cyclopropanation to the activated ester 2. The product 3…
Enantiomerically-enriched alkoxy stannanes such as 3 are versatile intermediates for synthesis. John R. Falck of UT Southwestern found(Angew. Chem. Int. Ed. 2008, 47, 6586.DOI: 10.1002/anie.200802313)that the simple combination of Bu3SnH…
Te that some allergens via protease- and TLRdependent mechanisms, which don’t involve down-regulation of TGF- or RALDH expression, can antagonize the tolerogenic function of lung tissue M for inducing Foxp3+…
Within the PCR array. Because qRT-PCR would be the accepted regular to compare transcript levels, these information suggest that E2 and 4-OHT might not significantly inhibit CTNNB1, IGFBP3 and AR…
(Cox), Salmochelin SX (Gagné), Botcinin F (Shiina), (-)-Saliniketal B (Paterson), Haterumalide NA (Borhan) Tohru Fukuyama of the University of Tokyo and Toshiyuki Kan of the University of Shizuoka devised (J.…
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