The thermal elimination of aryl sulfoxides is widely used, but requires elevated temperatures. Jun-ichi Matsuo and Hiroyuki Ishibashi of Kanazawa University have now shown (Org. Lett. Price of 168892-66-8 2006,…
A variety of effective strategies for catalytic enantioselective ring construction have recently been developed. The simplest approach is to start with a prochiral ring. Yian Shi of Colorado State University…
Five-membered cyclic ethers often do not show strong thermodynamic preferences. High diastereocontrol can, however, be achieved. Epoxy alkynes such as 1 can be prepared in high ee bySharpless epoxidation. Buy5-Azaspirooctane-6,8-dione…
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