Yan Qi and Yongjun Liu of the Qingdao University of Science and Technology demonstrated that the assembly of the tertiary alcohol 3 by the Barbier coupling of cyclohexanone 1 with…
Grubbs metathesis has proven to be a powerful tool for the rapid construction of complex heterocycles. Shengming Ma of the the Shanghai Institute of Organic Chemistry reports (J. Org. Methyl…
Following the Wenkert approach, Jun Huang and Zhen Yang of Peking University prepared the alkylated aldehyde 2 by conversion of the aldehyde 1 to the silyl enol ether, followed by…
Piperarborenine B (3), isolated from the stem of Piper arborescens, shows significant and selective antineoplastic activity. 2-(4,4-Difluorocyclohexyl)acetic acid site Andrey P. Antonchick of Nottingham Trent University constructed the cyclobutane core…
Are plated at a density of 16105 and quantified at day-to-day intervals. (E) Statistical analyses (n 3 independent samples per experiment) show that the numbers of cells per unit location…
As loading handle the expression of vinculin was usedkinase AKT (Figures 3 and 8c);47,48 and ERO1L expression, which controls the apoptotic process by escalating ROS levels and potentiating calcium release.49,50…
Hai-Chao Xu of Xiamen University used a phenothiazine-based catalyst to mediate the oxidative cyclization of the amide 1 to the cyclopropane 2 (J. Am. Chem. Soc. 2022, 144, 2343. DOI:…
Zheng Huang of the Shanghai Institute of Organic Chemistry showed that with an Ir catalyst, ethanol could serve as a reducing medium for the conversion of the alkyne 1 to…
Massimo Bietti of the Università "Tor Vergata" and Miquel Costas of the Universtat de Girona achieved substantial diastereoselectivity in the oxidative cyclization of the carboxylic acid 1 to the lactone…
Daniele Leonori, now at RWTH Aachen University, employed visible light to promote the Co-catalyzed elimination of the primary bromide 1 to the alkene 2 (J. 2091009-80-0 site Am. PMID:24211511 Chem.…
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