The first N-heterocycles prepared by alkene metathesis were simple five- and six-membered ring amides. Ring-closing metathesis of free amines is much more difficult. The diene 1, for instance, gave only…
Qiang Liu and Yibiao Li of Wuyi University developed a simple protocol for exchanging deuterium into the alkene 1, leading to 2 (Org. Lett. 2021, 23, 7412. DOI: 10.1021/acs.orglett.1c02600). Joseph…
Julian G. 61881-19-4 web West of Rice University used a vitamin B12-based catalyst to prepare the terminal alkene 2 by the elimination of the primary bromide 1 (Chem. PMID:31085260 Sci.…
Aristoquinoline (2), isolated from the leaves of the Maqui tree Aristotelia chilensis, was found to be a nicotinic acetylcholine receptor antagonist. BuyMethyl 6-aminopicolinate Buy130473-38-0 Keith P. Reber of Towson University…
Pepluanol A (3) was isolated from the European milkweed Euphorbia peplus. 957476-07-2 uses BuyLumisterol 3 (>90%) Tanja Gaich of the University of Konstanz devised a route to 3 based on…
N6 PUFAs in phospholipids (data not shown). Pearson correlation coefficient was calculated to assess correlation involving every PUFA. In phospholipids,Kume et al. Nutrition Metabolism 2013, 10:41 http://www.nutritionandmetabolism.com/content/10/1/Page 4 ofTable 1…
9111)) in staining medium (SM: clear MEM with supplements, 1 MEM (Invitrogen 51200), 10 mM Hepes (Invitrogen 15630), 1 GlutaMAX1 (Invitrogen 35050)) for 45 min. Cells were washed 4 times…
Oleg V. Larionov of the University of Texas at San Antonio used an acridine photocatalyst to mediate the decarboxylative conversion of the carboxylic acid 1 to the sulfonamide 2 (Chem.…
Christopher Uyeda of Purdue University reduced 1 to the intermediate vinylidene (also termed "alkylidene") carbene, that cyclized to the furan 2 (ACS Catal. 2021, 11, 193. DOI: 10.1021/acscatal.0c04713). Xinhao Zhang…
Pher G. Andersson of Stockholm University achieved high ee in the hydrogenation of the enone 1 to the ketone 2 (Org. 6-Bromo-2,3-dihydrobenzofuran manufacturer Fmoc-Phe(CF2PO3)-OH site Lett. PMID:23937941 2021, 23, 242.…
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