9111)) in staining medium (SM: clear MEM with supplements, 1 MEM (Invitrogen 51200), 10 mM Hepes (Invitrogen 15630), 1 GlutaMAX1 (Invitrogen 35050)) for 45 min. Cells were washed 4 times…
Oleg V. Larionov of the University of Texas at San Antonio used an acridine photocatalyst to mediate the decarboxylative conversion of the carboxylic acid 1 to the sulfonamide 2 (Chem.…
Christopher Uyeda of Purdue University reduced 1 to the intermediate vinylidene (also termed "alkylidene") carbene, that cyclized to the furan 2 (ACS Catal. 2021, 11, 193. DOI: 10.1021/acscatal.0c04713). Xinhao Zhang…
Pher G. Andersson of Stockholm University achieved high ee in the hydrogenation of the enone 1 to the ketone 2 (Org. 6-Bromo-2,3-dihydrobenzofuran manufacturer Fmoc-Phe(CF2PO3)-OH site Lett. PMID:23937941 2021, 23, 242.…
Sinupol (3), isolated from the soft coral Sinularia polydactyla, showed moderate inhibitory activity toward protein tyrosine phosphatase 1B. Koichiro Ota and Hiroaki Miyaoka of the Tokyo University of Pharmacy and…
Xiaobei Chen,Yanwei Hu and Shilei Zhang of Soochow University showed that the inexpensive calcium hydride could be used to reduce the aryl halide 1 to the arene 2 (Org. Chem.…
Bruce H. Lipshutz of the University of California, Santa Barbara developed surfactants that allowed the aqueous enzymatic reduction of the enone 1 to the ketone 2 (Chem. Commun. 2021, 57,…
Carbon-carbon bond formation is fundamental to all of organic chemistry. PMID:28440459 The emphasis this week is on recently-developed useful transformations that are easily scalable. Notably, these transformations telescope two or…
Rom 3 distinct donors. (, p 0.05; , p 0.01).ing resulted in a substantial enhance in STAT1 protein levels in these cells (Fig. 3F). Paralleling STAT1 protein levels, levels of…
Bbreviated as (CP/C), revealed the differential expression of 329 genes amongst the two biofilms (see Tables two, S4 and S5). Comparison of gene expression upon selfcolonization (CC/C experiment) and upon…
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