The prochiral aziridine 1 is easily prepared from cyclooctene. Paul Müller of the University of Geneva has shown (Helv. Chim. Buy362522-50-7 Acta 2004, 87, 227. DOI: 10.1002/hlca.200490010)that metalation of 1…
Imre Pápai and Tibor Soós of the Institute of Organic Chemistry, Budapest prepared the oxetane 3 by the relay ring-closing methathesis of the alkene 1 with the diene 2 (Angew.…
Joshua D. Sieber of Virginia Commonwealth University used a Cu catalyst to mediate the assembly of the protected amino alcohol 3 by the addition of the allenamide 2 to the…
Xiongjie Jin and Kyoko Nozaki of the University of Tokyo established an effective protocol for the hydrogenation of an ester 1 to the corresponding hydrocarbon 2 (J. Am. Chem. Soc.…
Petromyroxol (3) was isolated from > 106 liters of sea water conditioned with larval sea lamprey, Petromyzon marinus. Rodney A. Fernandes of the Indian Institute of Technology Bombay assembled the…
Qiwei Lang, Gen-Qiang Chen and Xumu Zhang of the Southern University of Science and Technology achieved high ee in the reduction of the readily available lactol 1 to the lactone…
Many of the five- and six-carbon sugars, although well known, are rare, and too expensive to be used as chiral pool starting materials. David MacMillan of Caltech in an elegant…
Christopher B. 2-Aminoacetamide uses Kelly of Janssen Discovery Process, Osvaldo Gutierrez of Texas A&M and Mark D. Levin of the University of Chicago used the N-acyloxy N-alkoxy amide 2 to…
Benjamin List of the Max-Planck-Institut für Kohlenforschung used a confined imidodiphosphorimidate to catalyze the cyclization of the unsaturated acid 1 to the lactone 2 (J. Am. Chem. Soc. 2023, 145,…
Kamebanin (3), isolated from the Japanese flowering plant Isodon kameba Okuyama (Isodon umbrosus), showed cytotoxic and antibiotic activity. Takahiro Suzuki and Keiji Tanino of Hokkaido University devised a route to…
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