Suzuki couplings using a microencapsulated palladium catalyst (Pd EnCat) under microwave heating were investigated by the group of Steven V. PMID:34856019 Ley at the University of Cambridge (Chem. 1450752-97-2 Purity…
Chi-Ming Che and co-workers from the University of Hong Kong have reported on the intra- and intermolecular hydroamination of unactivated alkenes (Org. Lett. 2006, 8, ASAP. DOI: 10.1021/ol060719x). In a…
Hartmut Schirok from Bayer HealthCare, Germany, has reported on a short and flexible synthesis of 1,3-substituted 7-azaindoles 2 starting from oxiranes 1 (J. PMID:23724934 Org. Chem. 2006, 71, 5538.DOI: 10.1021/jo060512h).…
Oliver Reiser and his group from the University of Regensburg, Germany have reported on the ring-closing metathesis (RCM) of a sterically demanding substrate in the context of the total synthesis…
Mohammad Movassaghi and Matthew D. Hill from MIT have developed a protocol for the synthesis of quinazolines 1 via electrophilic activiation of secondary amides utilizing 2-chloropyridine (2-ClPyr) in combination with…
A 144-member library of furocoumarins via three-component reaction of 4-hydroxycoumarins, isocyanides and arylaldehydes was prepared by Jie Wu from VivoQuest Inc., NY (Chem. Lett. 2006, 35, 118. (4-Chlorophenyl)(2-nitrophenyl)sulfane web DOI:…
Enzymes have many applications in organic synthesis. One of the most common is the resolution of a secondary alcohol. A shortcoming of this approach is that the separation of the…
Jie Yan and co-workers from Zhejiang University of Technology, China, have reported on Suzuki-type couplings in water without the use of catalyst and base (Eur. J. PMID:23558135 Org. P(t-Bu)3 Pd…
Sarah Mossé and Alexandre Alexakis from the University of Geneva have reinvestigated asymmetric aldol (a), Mannich (b) and Diels-Alder reactions (c) applying organocatalysis under microwave conditions (Org. PMID:23912708 Lett. BuyRuPhos…
The Diels-Alder reaction is a powerful tool for the construction of substituted cyclohexenes. Erik J. Formula of 1234616-36-4 Sorenson of Princeton University has developed (J. Am. 2-(2-Bromoethyl)oxirane Formula Chem. Soc.…
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