Developments in Alkene Metathesis
Chemexpress Hervé Clavier and Steven P. Nolan, now at St. Andrew’s University, found (Adv. Synth. Catal. 2008, 350, 2959.DOI: 10.1002/adsc.200800495)that the indenylidene Ru complex 1 was an excellent pre-catalyst for alkene…
Practical Enantioselective Construction of Arrays of Stereogenic Centers:
The Jørgensen Synthesis of the Autoregulator IM-2 Amando Córdova of Stockholm University found (Angew. Chem. Int. Ed. 2008, 47, 8468. DOI: 10.1002/anie.200802335) that the enantiomerically-enriched diastereomers from aminosulfenylation of 1…
Organocatalytic C-C Ring Construction: (+)-Ricciocarpin A (List) and (-)-Aromadendranediol
(MacMillan) Yoshiji Takemoto of Kyoto University designed (Org. 288617-73-2 Chemscene Lett. 2009, 11, 2425. DOI: 10.1021/ol9006053) an organocatalyst for the enantioselective conjugate addition of alkene boronic acids to γ-hydroxy enones,…
Preparation of Heteroaromatics
Masahiro Yoshida of the University of Tokushima described(Tetrahedron Lett. 2008, 49, 5021.DOI: 10.1016/j.tetlet.2008.06.043)the Pt-mediated rearrangement of alkynyl oxiranes such as 1to the furan 2. Roman Dembinski of Oakland University reported(J.…
Stereoselective C-O Ring Construction: The Oguri-Oikawa Synthesis of Lasalocid A
O-Centered radicals have been little used for C-O ring formation. PMID:24633055 Glenn M. Sammis of the University of British Columbia showed (Org. Lett. 2008, 10, 5083 DOI: 10.1021/ol802142k) that O-centered…
So et al., 2006). Taking into consideration the micromolar concentrations of nitrate out there in
So et al., 2006). Thinking of the micromolar concentrations of nitrate out there inside the aquifer (Williams et al., 2011), this might also reasonably clarify the enrichment of bacteria in…
Icentric, randomized, controlled trial to assess blood glucose control through the
Icentric, randomized, controlled trial to evaluate blood glucose management through the model predictive management algorithm versus regimen glucose management protocols in intensive care unit sufferers. Diabetes Care 2006, 29(2):271-276. 44.…
Substituted Benzenes: The Alvarez-Manzaneda Synthesis of (-)-Taiwaniquinone
G Continuing efforts toward the direct functionalization of aromatic C-H bonds, Nobutaka Fujii and Hiroaki Ohno of Kyoto University described (Chem. Commun. 2009, 3413. DOI: 10.1039/b905586j) a Pd-mediated protocol for…
Advances in Alkene and Alkyne Metathesis
As alkene metathesis is extended to more and more challenging substrates, improved catalysts and solvents are required. Robert H. 233276-38-5 manufacturer Grubbs of Caltech developed (Org. Lett. tBuBrettPhos Pd G3…
Alkaloid Synthesis: (-)-Aurantioclavine (Stoltz), (-)-Esermethole (Nakao/Hiyama/Ogoshi),
(-)-Kainic Acid (Tomooka), Dasycarpidone (Bennasar), (-)-Cephalotaxine (Ishibashi) and Lysergic Acid (Fujii/Ohno) Intriguing strategies have been developed for the stereocontrolled assembly of complex alkaloid structures. Brian M. Stoltz of Caltech prepared…