Massimo Bietti of the Università "Tor Vergata" and Miquel Costas of the Universtat de Girona achieved substantial diastereoselectivity in the oxidative cyclization of the carboxylic acid 1 to the lactone…
A. PMID:28739548 Fmoc-Phe-OH Chemscene Venkat Narsaiah of CSIR-Indian Institute of Technology, Hyderabad selectively removed one of the silyl ethers of 1, to give 2 (Tetrahedron Lett. 2021, 82, 153410. DOI:…
Melicodenine C (4) was isolated from the leaves of Melicope denhamii, a rutaceous shrub found in Borneo that has been used in indigenous medicine. PMID:23892407 John R. Swierk of Binghamton…
Alois Fürstner of the Max-Planck-Institut für Kohlenforschung set the relative and absolute configuration of 3 by the Ni-mediated addition of the enol ether 2 to the aldehyde 1 (J. Am.…
Delicato Dipartimento di Scienze e Tecnologie Biologiche, ` Chimiche, Farmaceutiche, Universita di Palermo, Parco Orleans II, Ed. 17, 1690128 Palermo, Italy e mail: [email protected] R. Indelicato S. Barreca ` Dipartimento…
Y by improved apoptosis within a Rho/Rhoassociated kinase (ROCK)dependent mechanism. Moreover, LPA inhibited the neuronal differentiation of iPSCs. Lastly, LPA induced neurite retraction of NS/ PCderived early neurons via Rho/ROCK,…
Shouyun Yu of Nanjing University devised a protocol for the distal dehydrogenation of the acyloxyamide 1 to the alkene 2 (Org. Lett. 2021, 23, 6931. DOI: 10.1021/acs.orglett.1c02509). Armido Studer of…
The first N-heterocycles prepared by alkene metathesis were simple five- and six-membered ring amides. Ring-closing metathesis of free amines is much more difficult. The diene 1, for instance, gave only…
Yasuharu Yoshimi of the University of Fukui devised a photocatalyst that efficiently promoted the coupling of the acid 1 with acrylonitrile 2, to give, with the net addition of two…
Julian G. 61881-19-4 web West of Rice University used a vitamin B12-based catalyst to prepare the terminal alkene 2 by the elimination of the primary bromide 1 (Chem. PMID:31085260 Sci.…
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