Alison E. Buy103128-76-3 Wendlandt of MIT devised a protocol for the contrathermodynamic isomerization of the alkene 1 to the alkene 2 (J. Am. Chem. Soc. 2022, 144, 145. DOI: 10.1021/jacs.1c12043).…
Yasunori Toda and Hiroyuki Suga of Shinshu University achieved high regioselectivity in the conversion of the epoxide derived from 1 to the oxazoline 2 (Chem. Commun. 3-(4-Fluorophenoxy)azetidine Order 2022, 58,…
Rameswaralide (4), isolated from the soft coral Sinularia dissecta, showed modest cytotoxicity. 2411793-14-9 supplier In the course of a synthesis of 4, Daniel Romo of Baylor University showed that with…
Indolizidine 209D (3), isolated from the neotropical "poison dart" frog, inhibits neuromuscular transmission. Hanyue Qiu, Ling He and Min Zhang of Chongqing University rearranged the cyclopropanol 1, prepared from the…
Ai-Lan Lee of Heriot-Watt University developed a protocol for the decarboxylation of the carboxylic acid 1 to the hydride 2 (Org. Lett. 2022, 24, 686. DOI: 10.1021/acs.orglett.1c04079). Joseph R. Clark…
Histology of proximal tibia showed important decreases in MS/BS, MAR and BFR/BS in the OVX rats compared with the sham, plus the CFE group totally maintained these parameters for the…
Lbeit to a lesser extent than with phenformin, and DHAP and glyceraldehyde3phosphate are slightly decreased. Neither biguanide has an impact around the earliest glycolytic intermediates that are elevated during transformation…
Pher G. Andersson of Stockholm University showed that a Z/E mixture of the enone 1 could be hydrogenated to 2 in high ee (Nature Commun. 2022, 13, 361. DOI: 10.1038/s41467-022-28003-6).…
Jin-Na Song of Jilin University and Yongquan Ning of Northeast Normal University assembled the furan 3 by combining the diazoalkane derived in situ from the tosylhydrazone 2 with the β-keto…
Liang-Nian He of Nankai University and Chao-Jun Li of McGill University converted the hydrazone of carvone 1 to the triene 2 (JACS Au 2022, 2, 1929. DOI: 10.1021/jacsau.2c00320). Mathias Schelwies…
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