Stefan Schulz of the Technische Universität Braunschweig updated the classic intramolecular Diels-Alder cycloaddition of the triene 1 to the ketone 2, readily convertible to δ-cadinol (3), by preparing 1 via…
Xufeng Lin of Zhejiang University used an enantiomerically-pure bis iodide to mediate the oxidative cyclization of the prochiral amine 1 to the lactam 2 (Tetrahedron Lett. 2022, 109, 154157. DOI:…
Efficient new methods for oxidation are always welcome. The Dess-Martin periodinane has become the workhorse for alcohol to aldehyde or ketone conversion in organic research labs around the world. 5-Azaspirooctane-6,8-dione…
(-)-Podophyllotoxin 1 and its derivative etoposide 2, derived from natural sources, are in current clinical use. Michael Sherburn of Australian National University reports (J. PMID:23618405 Am. 2-Methylpyrimidine-5-carbaldehyde custom synthesis Chem.…
Nt (Table S1 in the Supporting Information and facts). The omit density map shows a single Mn(II) ion (Mn1) within a tetrahedral coordination complex with three amino acid residues (Cys98,…
:10.1371/journal.pone.0079682.tPLOS 1 | www.plosone.orgHeritability of Uremic Retention MoleculesTable two. Baseline qualities by quartiles of pcresyl sulfate.PCresyl Sulfate, mmol/L Characteristics Qualities n ( ) Males Hypertension Antihypertensive drug intake Diabetes mellitus…
Tabertinggine (4) was isolated from the Mayasian shrub Tabernaemontana corymbosa, the dwarf pinwheel. Xuegong She of Lanzhou University assembled the key tetracyclic intermediate 3 by the BINOL-derived phosphoric acid mediated…
Kegong Ji of the Northwest Agricultural & Forestry University used a Cu catalyst to cyclize the alkyne 1 to the furan 2 (Org. 8-Hydroxyoctanoic acid In stock Chem. Front. 2023,…
Spirooliganone A (Morita), Microansamycin H (Sittihan), Gymnothelignan N (Lee), 3(11)-Epoxyhypoestenone (Wang/Chen) Ophiofuranone A (3) was isolated from the endolichenic fungus Ophiospaerella korrae. Rainer Schobert of the University Bayreuth prepared the…
Spiroapplanatumine O (3) was isolated from Ganoderma applantum, a wood-decaying fungus that is widely used in traditional medicinal chemistry. Ullrich Jahn of the Institute of Organic Chemistry and Biochemistry of…
Chemexpress