Product Name :
2-Oleoylglycerol (CAS 3443-84-3)
Synonym :
2-Monoolein
Application :
2-Oleoylglycerol is a GPR119 agonist that regulates GLP-1 release
CAS:
3443-84-3
Purity:
≥95%
Molecular Weight:
356.54
Formula :
C21H40O4
Physical state:
Low-Melting Solid
solubility :
Shipping Condition :
Store at -20° C
Melting point:
22-23.5° C
SMILES:
CCCCCCCC/C=C\\CCCCCCCC(=O)OC(CO)CO
References:
:Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerol. | Ghafouri, N., et al. 2004. Br J Pharmacol. 143: 774-84. PMID: 15492019Cyclooxygenation of the arachidonoyl side chain of 1-arachidonoylglycerol and related compounds block their ability to prevent anandamide and 2-oleoylglycerol metabolism by rat brain in vitro. | Fowler, CJ. and Tiger, G. 2005. Biochem Pharmacol. 69: 1241-5. PMID: 15794945Lack of selectivity of URB602 for 2-oleoylglycerol compared to anandamide hydrolysis in vitro. | Vandevoorde, S., et al. 2007. Br J Pharmacol. 150: 186-91. PMID: 17143303Circadian rhythm of circulating levels of the endocannabinoid 2-arachidonoylglycerol. | Hanlon, EC., et al. 2015. J Clin Endocrinol Metab.4-Amino-6-chloropyrimidin-5-ol supplier 100: 220-6.417727-40-3 Chemscene PMID: 25368979Where′s my entourage? The curious case of 2-oleoylglycerol, 2-linolenoylglycerol, and 2-palmitoylglycerol. | Murataeva, N.PMID:33741299 , et al. 2016. Pharmacol Res. 110: 173-180. PMID: 27117667Evolution of the diacylglycerol lipases. | Yuan, D., et al. 2016. Prog Lipid Res. 64: 85-97. PMID: 27568643Synthesis of 1,3-distearoyl-2-oleoylglycerol by enzymatic acidolysis in a solvent-free system. | Wang, X., et al. 2017. Food Chem. 228: 420-426. PMID: 28317743Endocannabinoid and Opioid System Interactions in Exercise-Induced Hypoalgesia. | Crombie, KM., et al. 2018. Pain Med. 19: 118-123. PMID: 28387833Olfactory connectivity mediates sleep-dependent food choices in humans. | Bhutani, S., et al. 2019. Elife. 8: PMID: 31591965Neuroprotective Effect of 1,3-dipalmitoyl-2-oleoylglycerol Derived from Rice Bran Oil against Cerebral Ischemia-Reperfusion Injury in Rats. | Lee, HK., et al. 2022. Nutrients. 14: PMID: 35405992Oxidative lipidomics to elucidate the non-volatile derivatives of four typical triglycerides in vegetable oils under simulated frying conditions. | Hu, Q., et al. 2023. Food Chem. 410: 135414. PMID: 36638631Western diet contributes to the pathogenesis of non-alcoholic steatohepatitis in male mice via remodeling gut microbiota and increasing production of 2-oleoylglycerol. | Yang, M., et al. 2023. Nat Commun. 14: 228. PMID: 366467152-Arachidonoylglycerol, a putative endogenous cannabinoid receptor ligand, induces rapid, transient elevation of intracellular free Ca2+ in neuroblastoma x glioma hybrid NG108-15 cells. | Sugiura, T., et al. 1996. Biochem Biophys Res Commun. 229: 58-64. PMID: 8954083