Product Name :
Urokinase Rabbit Polyclonal Antibody
Predicted band size :
49 kDa
Observed band size :
56 kDa
Synonyms:
ATF antibody ATF uPA antibody BDPLT5 antibody Plasminogen activator antibody Plasminogen activator urinary antibody Plasminogen activator urokinase antibody PLAU antibody QPD antibody u PA antibody U plasminogen activator antibody 展开
Function :
Urokinase, also known as urokinase-type plasminogen activator (uPA), is a serine protease present in humans and other animals. The human urokinase protein was discovered, but not named, by McFarlane and Pilling in 1947.1780038-41-6 Chemscene Urokinase was originally isolated from human urine, and it is also present in the blood and in the extracellular matrix of many tissues. The primary physiological substrate of this enzyme is plasminogen, which is an inactive form (zymogen) of the serine protease plasmin. Activation of plasmin triggers a proteolytic cascade that, depending on the physiological environment, participates in thrombolysis or extracellular matrix degradation. This cascade had been involved in vascular diseases and cancer progression. Urokinase is encoded in humans by the PLAU gene, which stands for “plasminogen activator, urokinase”. The same symbol represents the gene in other animal species.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Recombinant protein within Human Urokinase 10- 200 aa
Species reactivity:
Human, Rat
Verify application:
WB, IF-Cell
Coupling :
unconjugated
Clone number:
RRID:
AB_3071514
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.914224-26-3 uses Aliquot store at -20℃.PMID:33674871 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 49 kDa
Positive control :
PC-3M cell lysate, MCF-7 cell lysate, LANCAP cell lysate, rat kidney tissue lysate, rat stomach tissue lysate, PC-3M.