Product Name :
PTBP1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
57 kDa RNA binding protein PPTB 1 antibody 57 kDa RNA-binding protein PPTB-1 antibody Heterogeneous nuclear ribonucleoprotein I antibody Heterogeneous Nuclear Ribonucleoprotein Polypeptide I antibody hnRNP I antibody HNRNP-I antibody HNRNPI antibody HNRPI antibody MGC10830 antibody MGC8461 antibody 展开
Function :
Polypyrimidine tract-binding protein 1 is a protein that in humans is encoded by the PTBP1 gene. It plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. PTBP1 activates exon skipping of its own pre-mRNA during muscle cell differentiation. It binds to the polypyrimidine tract of introns and may promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. PTBP1 may promote the binding of U2 snRNP to pre-mRNA. It cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide corresponding to Human PTBP1 aa 1-50 / 531.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
AB_3073291
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃.Buy1257856-15-7 Avoid repeated freeze / thaw cycles.Medronic acid supplier
Storage buffer solution:
1*PBS (pH7.PMID:33723835 4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 60 kDa
Positive control :
Jurkat, Daudi, A549, rat heart, PC12, NIH/3T3, F9, Hela , mouse testis