Renat Kadyrov of Evonik Degussa and Magnus Rueping of RWTH Aachen developed (Angew. Chem. Int. Ed. 2009, 49, 7556. DOI: 10.1002/anie.200902835) an effective catalyst for the enantioselective hydrogenation of an…
Arene diazonium salts are effective precursors for the Heck reaction. Sandro Cacchi of the Università degli Studi “La Sapienza”, Roma, observed(Synlett 2009, 1277.DOI: 10.1055/s-0028-1088132)that the diazonium salt generated in situ…
Jianbo Wang of Peking University described (Angew. Chem. Int. Ed. 2010, 49, 2028. DOI: 10.1002/anie.200906699) the Au-promoted bromination of a benzene derivative such as 1 with N-bromosuccinimide. In a one-pot…
There are two major impediments to the scaling up of alkene metathesis, reducing the amount of the expensive Ru catalyst required, and minimizing residual Ru in the product. Robert H.…
(-)-Adaline (Yu), (-)-Securinine (Bayón/Figueredo), Alkaloid 223A (Aubé), (-)-Huperzine A (Fukuyama) The recent development of practical methods for the asymmetric preparation of amines has enabled creative approaches to alkaloid construction. Cyclopropylmethyl…
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