Helionine (3) was isolated from the Chinese lily Fritillaria ussuriensis, used in traditional medicine. Viresh H. Buy1,3,5-Tri(pyridin-4-yl)benzene Rawal of the University of Chicago devised a convergent approach to 3, based…
Maurizio Botta and his group from the University of Siena, Italy have employed microwave mediated ethylene-alkyne cross-metathesis using Grubbs 2 catalyst for the synthesis of enantioenriched 2-substituted butadiens (Tetrahedron: Asymmetry…
Jie Wu of Taizhou University prepared the vinyl sulfone 3 by coupling the tertiary propargylic alcohol 1 with the diazonium salt 2 in the presence of sodium metabisulfite (Adv. Synth.…
Mitrephorone A (Carreira) The crotonate ester COTC (3), an inhibitor of alkaline phosphodiesterase isolated from a soil Streptomyces, had cytotoxic and cancerostatic activity. Szymon Buda of Jagiellonian University prepared the…
Gullapalli Kumaraswamy of the Indian Institute of Chemical Technology assembled the cyclopropane 3 by the (DHQD) Pyr-mediated addition of the bromo amide 2 to the enone 1 (Tetrahedron 2021, 87,…
Antibody (Abcam; Ab13509; 1:200) or even a standard rabbit IgG (Santa Cruz Biotechnology; 1:100) was incubated using the cell lysate and with 40 L protein A agarose beads (Roche). The…
Occupy the complementary S4 and S1 subsites, respectively. Acidic residues are shown in orange; Glu79 at the P2 position and Glu85 in the P4 position are close to CTRC regions…
D CTRC Ser214 (Ser236) (Fig. 2C). The Leu45 carbonyl oxygen is positioned to interact with the CTRC oxyanion hole amide nitrogens of Ser195 (Ser216) and Gly193 (Gly214). Around the primed…
. main compared with theophylline, avert histopathological alterations of lung in asthmatic rats. The effect can be due to Tanen and Mucilage. Antiinflammatory, analgesic, antioxidant, immunomodulating and antiulcerogenic activity of…
Y highperformance liquid chromatography (HPLC) as previously described (see supplemental information in Distler et al., 2012). Statistical analyses All statistical analyses were performed working with StatView for Windows (SAS Institute,…
Chemexpress