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Functional Group Interconversion: The Hirose/Sunazuka Synthesis of Luminamicin

Chemexpress March 31, 2024 0 Comments

Qiao-qiao Teng and Ming Chen of Changzhou University showed that barium oxide is a strong enough base to doubly deuterate an alkyl nitrile 1, leading to 2 (Eur. J. 1196154-13-8…

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Functional Group Protection: The Carreira/Piel Synthesis of Janustatin A

Chemexpress March 31, 2024 0 Comments

Hiroki Mandai of the Gifu University of Medical Science and Seiji Suga of Okayama University devised conditions to selectively protect the phenol of diol 1, leading to 2 (Chem. Lett.…

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Other Methods for C-C Ring Construction: Scabrolide A (Sarlah), Clovan-2,9-dione (Newhouse), Gibberellin A18 (Dai), Isoneoamphilectane (Vanderwal), Stelletin E (Jiao/Xie), Puberuline C (Inoue)

Chemexpress March 31, 2024 0 Comments

Scabrolide A (3), isolated from the soft coral Sinularia scabra, has both anticancer and anti-inflammatory activity. PMID:24078122 En route to 3, David Sarlah of the University of Illinois cyclized the…

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Arrays of Stereogenic Centers: The Tanaka/Kitamura Synthesis of Pancratistatin

Chemexpress March 31, 2024 0 Comments

Jin Kun Cha of Wayne State University achieved high diastereoselectivity in the reductive addition of the propargyl ether 1 to the aldehyde 2, to give the 1,6-diol 3 (Org. Lett.…

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C-H Functionalization: The Zhu Synthesis of β-Cuparenone

Chemexpress March 31, 2024 0 Comments

Soon Hyeok Hong of KAIST devised the photochemically-promoted coupling of the acid chloride 2 with the hydrocarbon 1, leading to the ketone 3 as a mixture of diastereomers (Nature Commun.…

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NtPLOS A single | www.plosone.orgLipoprotein Profiles in Mice with Humanized Livershuman

Chemexpress March 30, 2024 0 Comments

NtPLOS 1 | www.plosone.orgLipoprotein Profiles in Mice with Humanized Livershuman FGF19 (PeproTech, Catalog # 10032) was reconstituted in 0.9 saline with 0.1 BSA and three humanized and 3 manage FRGN…

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Acterial virulence around the Arabidopsis ecotype Columbia or the tomato `Moneymaker

Chemexpress March 30, 2024 0 Comments

Acterial virulence on the Arabidopsis ecotype Columbia or the tomato `Moneymaker’ cultivar (Wei et al., 2007). So that you can identify much more robust diseaserelated phenotypes, we generated transgenic dexamethasone…

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Carbon-Carbon Bond Formation: The Kalesse Synthesis of Illisimonin A

Chemexpress March 30, 2024 0 Comments

Biplap Maji of the Indian Institute of Science Education and Research Kolkata prepared the α-hydroxy acid 3 by combining the primary alcohol 1 with ethylene glycol 2 (Angew. Chem. Formula…

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Enantioselective Construction of Single Stereogenic Centers

Chemexpress March 30, 2024 0 Comments

Single enantiomer synthesis is of increasing importance in pharmaceutical production. It is essential that practical and scalable procedures be developed for controlling the absolute configuration of new stereogenic centers as…

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Reactions of Alkenes: The Chida Synthesis of Paclitaxel (Taxol®)

Chemexpress March 30, 2024 0 Comments

Alison E. Buy103128-76-3 Wendlandt of MIT devised a protocol for the contrathermodynamic isomerization of the alkene 1 to the alkene 2 (J. Am. Chem. Soc. 2022, 144, 145. DOI: 10.1021/jacs.1c12043).…

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T of safer drugs. The outcomes demonstrated that each the models

Uncategorized

Levels. We used the model to study the effect of folate

Uncategorized

GjUGT2 amino acid sequence as a query. From an initial list

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Thylsubstituted diyne 6d cyclized with 1hexyne 9a to form a 9:1 mixture

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