The maleic anhydride derivative triciadolide C (3) was isolated from the aquatic hyphomycete Tricladium castaneicola. PMID:23460641 Shaozhong Wang of Nanjing University developed a general route to such anhydrides, exemplified by…
John C. Jewett of the University of Arizona demonstrated that the protected diazonium salt 1 participated efficiently in Suzuki coupling, leading the biphenyl 2 (Org. Lett. 2021, 23, 1851. DOI:…
Post. This study confirmed the protective impact of butorphanol postC on ischaemic myocardium in reperfusion injury. We used 50 g kg1 of butorphanol primarily based on our earlier report that…
The cells have been transfected with TRPC3 siRNA as described above and starved overnight before incubation with FSH for an added 48 hr. Cisplatin was added at a final concentration…
Guosheng Liu of the Shanghai Institute of Organic Chemistry devised the enantioselective Pd-catalyzed diacetoxylation of the alkene 1 to the bis-acetate 2 (Nature Catal. 2021, 4, 172. DOI: 10.1038/s41929-021-00574-5). Bingxian…
Because the stereocontrolled construction of cyclic ethers has been difficult and expensive, the use of cyclic ethers as pharmaceuticals has not been fully explored. 1,2,3,4-Tetrahydrobenzoquinoline Chemical name With the development…
Duen-Ren Hou of the National Central University devised a simple protocol for the direct acetoxylation of the substituted benzene 1, leading to the aryl acetate 2 (Org. Lett. 2021, 23,…
Xihe Bi of Northeast Normal University showed that the diazo alkane generated in situ from the sulfonylhydrazide 2 could with a silver catalyst be added to the alkene 1, to…
Chen Xu of the Southern University of Science and Technology and Zheng Huang of the Shanghai Institute of Organic Chemistry effected the acceptorless photochemical dehydrogenation of the sulfide 1 to…
Aaron Aponick of the University of Florida achieved high ee in the cyclization of the allylic alcohol 1 to the lactone 2 (Angew. Chem. Int. Ed. 2021, 60, 22224. DOI:…
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