Hongjian Lu of Nanjing University used an Ir catalyst to mediate the regioselective ortho amination of the benzamide 1, leading to the protected anthranilamide 2 (J. Org. 574007-66-2 structure Chem.…
Oleg V. Larionov of the University of Texas at San Antonio devised a protocol for the decarboxylative coupling of an acid 1 with an arenesulfinate 2 to give the sulfoxide…
Carbocyclic rings, unlike saturated heterocyclic rings, are not susceptible to the hepatic activation that is the basis of much drug toxicity. To pave the way for pharmaceutical discovery based on…
Christopher Uyeda of Purdue University achieved high enantioselectivity in the cyclopropanation of myrcene (1) with 2,2-dichloropropane (2) to give 3 (J. Am. Chem. Soc. 2023, 145, 9441. DOI: 10.1021/jacs.3c01949). Qinglei…
Malte Brasholz of the University of Rostock developed a protocol for the photochemically-driven in situ oxidation of the quinoxalinone 1 followed by cycloaddition with methacrylonitrile 2 to give the azetidine…
Vicente Gotor-Fernández and Iván Lavandera of the Universidad de Oviedo optimized the enzymatic reduction of the chloroketone 1 to the chlorohydrin 2, then telescoped that to begin with the 1-chloroalkyne…
two.five L) and terminal TdT (25 Units) in buffer (Promega, Madison, WI). Cellspecific immunohistochemical labeling was performed as previously described (Guyton et al. 2009). Briefly, before primary antibody staining, nonspecific…
The logistic regression evaluation revealed that being an injection drug user (IDU) was substantially related to HCV infection. Having said that, contrary to the majority of the existing literature, getting…
Haibo Ge of Texas Tech University and Debabrata Maity of the Indian Institute of Technology Bombay effected the m-acetoxylation of the ester 1, leading to 2 (JACS Au 2023, 3,…
Arjan W. Kleij of ICIQ optimized an aluminum catalyst for the conversion of the bis epoxide 1 to the oxetane 2 (ACS Catal. PMID:23399686 2022, 12, 5464. DOI: 10.1021/acscatal.2c00925). A.…
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