Product Name :
VRK1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
MGC117401 antibody MGC138280 antibody MGC142070 antibody PCH1 antibody PCH1A antibody Serine/threonine protein kinase VRK1 antibody Serine/threonine-protein kinase VRK1 antibody Vaccinia related kinase 1 antibody Vaccinia virus B1R related kinase 1 antibody Vaccinia-related kinase 1 antibody 展开
Function :
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthesized peptide derived from part region of human protein
Species reactivity:
Human, Mouse
Verify application:
WB
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.2-Amino-3-bromo-5-chlorobenzoic acid In stock Aliquot store at -20℃ or -80℃.4-Bromo-2-methylpyrimidine web Avoid repeated freeze / thaw cycles.PMID:33545151
Storage buffer solution:
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
43 kDa
Positive control :
Brain,Fetal liver,Lung,