Product Name :
SMURF1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
E3 ubiquitin-protein ligase SMURF1 antibody hSMURF1 antibody KIAA1625 antibody Smad specific E3 ubiquitin ligase 1 antibody SMAD specific E3 ubiquitin protein ligase 1 antibody Smad ubiquitination regulatory factor 1 antibody SMAD-specific E3 ubiquitin-protein ligase 1 antibody SMUF1_HUMAN antibody SMURF 1 antibody smurf1 antibody
Function :
E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Promotes ubiquitination and subsequent proteasomal degradation of MAVS . Plays a role in dendrite formation by melanocytes .
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within human SMURF1 aa 30-80.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB
Coupling :
unconjugated
Clone number:
RRID:
AB_3071157
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Dimethyl pimelate structure Aliquot store at -20℃.951173-34-5 Chemical name Avoid repeated freeze / thaw cycles.PMID:33733305
Storage buffer solution:
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size:86 kDa
Positive control :
NIH/3T3 cell lysate, MCF-7 cell lysate, rat kidney tissue lysate.