Product Name :
2-thio PAF (CAS 96801-55-7)
Synonym :
1-O-hexadecyl-2-deoxy-2-thio-S-acetyl-sn-glyceryl-3-phosphorylcholine
Application :
2-thio PAF is an isosteric analog of PAF
CAS:
96801-55-7
Purity:
Molecular Weight:
539.75
Formula :
C26H54NO6PS
Physical state:
Liquid
solubility :
Shipping Condition :
Store at -80° C
Melting point:
SMILES:
CCCCCCCCCCCCCCCCOCC(COP(=O)(O)OCC[N+](C)(C)C)SC(=O)C
References:
:PAF levels and PAF-AH activities in placentas from normal and preeclamptic pregnancies. | Gu, Y., et al. 2006. Placenta. 27: 744-9. PMID: 16122793Plasma PAF-acetylhydrolase activity, inflammatory markers and susceptibility of LDL to in vitro oxidation in patients with type 1 diabetes mellitus.Formula of 1257850-86-4 | Gomes, MB., et al. 2009. Diabetes Res Clin Pract. 85: 61-8. PMID: 19464746Serum platelet-activating factor acetylhydrolase activity: relationship with metabolic syndrome in women with history of gestational diabetes mellitus. | Derbent, A., et al. 2011. Gynecol Endocrinol. 27: 128-33. PMID: 20504094Membrane lipid composition differentially modulates the function of human plasma platelet activating factor-acetylhydrolase. | Pande, AH. and Tillu, VA. 2011. Biochim Biophys Acta. 1811: 46-56. PMID: 20869463The activity of platelet activating factor-acetyl hydrolase (PAF-AH) in the salivary glands of Rhodnius prolixus. | Côrte-Real, R., et al. 2011. J Insect Physiol. 57: 825-9. PMID: 21439293Inhibition of lipoprotein-associated phospholipase A2 ameliorates inflammation and decreases atherosclerotic plaque formation in ApoE-deficient mice. | Wang, WY., et al. 2011. PLoS One. 6: e23425. PMID: 21909350Group A Streptococcus secreted esterase hydrolyzes platelet-activating factor to impede neutrophil recruitment and facilitate innate immune evasion.(S)-2-Methylpiperidine hydrochloride custom synthesis | Liu, M., et al. 2012. PLoS Pathog. 8: e1002624. PMID: 22496650Determination of phospholipase activity of PAF acetylhydrolase. | Stafforini, DM. and McIntyre, TM. 2013. Free Radic Biol Med. 59: 100-7. PMID: 22659315LDL subclasses and lipoprotein-phospholipase A2 activity in suppressed HIV-infected patients switching to raltegravir: Spiral substudy. | Saumoy, M., et al. 2012. Atherosclerosis.PMID:33465489 225: 200-7. PMID: 23017355Characterization of streptococcal platelet-activating factor acetylhydrolase variants that are involved in innate immune evasion. | Liu, G., et al. 2013. Infect Immun. 81: 3128-38. PMID: 23774595Development of a seaweed derived platelet activating factor acetylhydrolase (PAF-AH) inhibitory hydrolysate, synthesis of inhibitory peptides and assessment of their toxicity using the Zebrafish larvae assay. | Fitzgerald, C., et al. 2013. Peptides. 50: 119-24. PMID: 24140404A rationally designed mutant of plasma platelet-activating factor acetylhydrolase hydrolyzes the organophosphorus nerve agent soman. | Kirby, SD., et al. 2015. Biochim Biophys Acta. 1854: 1809-1815. PMID: 26343853Atherogenic properties of LDL particles after switching from Truvada or Kivexa plus lopinavir/r to lamivudine plus lopinavir/r: OLE-MET substudy. | Saumoy, M., et al. 2017. HIV Clin Trials. 18: 49-53. PMID: 28081673