Thylsubstituted diyne 6d cyclized with 1hexyne 9a to form a 9:1 mixture
Chemexpress Thylsubstituted diyne 6d cyclized with 1hexyne 9a to form a 9:1 mixture of regioisomeric isoindolinones 15a and 16a (entry 1). Ethylsubstituted diyne 6e reacted with 1hexyne 11a with reduce regioselectivity,…