6,11-Epoxyisodaucane (3) was isolated from the liverwort Tritomaria polita. In the course of the synthesis of 3, a key step of which was the decyanative cyclization of the epoxide 1…
Rong-Jie Chein of the Academia Sinica, Taipei used the known (S)-(thiolan-2-yl) diphenylmethanol benzyl ether to catalyze the Johnson-Corey-Chaykovsky cyclopropanation of the enone 1 with the allylic bromide 2 to give…
eight(6814):86064. 42. Nijenhuis WA, Garner KM, van Rozen RJ, Adan RA (2003) Poor cell surface expression of human melanocortin4 receptor mutations related with obesity. J Biol Chem 278(25):229392945. 43. Windahl…
Ivation from shortterm latency. To confirm that fibroblasts had been productively infected, viral IE1 expression was validated by fluorescence microscopy (Fig. 1E). Similarly, lytic gene expression was observed when latently…
Elena V. PMID:32472497 5-Bromo-1,3-thiazole-2-carbaldehyde supplier Gusvskaya of the Universidade Federal de Minas Gerais and Matthias Beller of the Leibniz-Institut für Katalyse e.V. used benzaldehyde to convert the alcohol 1 to…
Shyam Sathyamoorthi of the University of Kansas showed that the epoxide 1 could be cyclized to the differentially-protected triol 2 (Org. Lett. 2022, 24, 939. DOI: 10.1021/acs.orglett.1c04310). David J. Aitken…
Qiao-qiao Teng and Ming Chen of Changzhou University showed that barium oxide is a strong enough base to doubly deuterate an alkyl nitrile 1, leading to 2 (Eur. J. 1196154-13-8…
Hiroki Mandai of the Gifu University of Medical Science and Seiji Suga of Okayama University devised conditions to selectively protect the phenol of diol 1, leading to 2 (Chem. Lett.…
Scabrolide A (3), isolated from the soft coral Sinularia scabra, has both anticancer and anti-inflammatory activity. PMID:24078122 En route to 3, David Sarlah of the University of Illinois cyclized the…
Jin Kun Cha of Wayne State University achieved high diastereoselectivity in the reductive addition of the propargyl ether 1 to the aldehyde 2, to give the 1,6-diol 3 (Org. Lett.…
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