Centration-dependent manner (Figure 3D, ideal) that peaked 24 hours immediately after the commence of treatment.5-FU Effects on Pim-1 Expression Are Mediated by miR-15bTo address the 5-FU ediated up-regulation of Pim-1…
Synthesis of (-)-Lasiol Hisashi Yamamoto of the University of Chicago devised (J. Am. Chem. Soc. 2010, 132, 7878. DOI: 10.1021/ja100951u) catalyst systems for the enantioselective epoxidation of a Z-homoallylic alcohol…
Stephen L. Buchwald of MIT established (J. Am. Buy885588-14-7 Chem. Soc. 2010, 132, 14076. DOI: 10.1021/ja107481a) a Pd-catalyzed protocol for conversion of an aryl triflate 1 to the halide 2.…
We found (Tetrahedron Lett. PMID:36014399 2010, 51, 3545. DOI: 10.1016/j.tetlet.2010.04.129) that the superiority of KH over NaH in the Williamson ether synthesis was particularly marked with congested partners such as…
B Jinxing Ye of the East China University of Science and Technology used (Tetrahedron Lett. PMID:23399686 Formula of 240401-09-6 2011, 52, 2715. DOI: 10.1016/j.tetlet.2011.03.079) the Hayashi catalyst to direct the…
Takashi Ooi of Nagoya University effected (J. Am. Chem. PMID:23847952 Soc. 2010, 132, 12240. DOI: 10.1021/ja105945z) the enantioselective protonation of ketene silyl acetals such as 1 to give 2 in…
Liming Zhang of the University of California, Santa Barbara described (J. Am. Chem. Soc. (R)-2-amino-1-phenylethan-1-ol manufacturer 2010, 132, 8550. DOI: 10.1021/ja1033952) the remarkable transformation of a propargyl alcohol 1 into…
Carrying out organic synthesis with a flow reactor can offer significant advantages over the more conventional batch processing. Andreas Kirschning of Leibniz Universität Hannover concisely summarized (Chem. Commun. 2011, 47,…
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