Xiaoxia Ye of Wenzhou Medical University and Jun Jiang of Wenzhou University used the barium salt of proline to direct the aldol reaction of the prochiral cyclobutanone 1 with the…
Yiyun Chen of the Shanghai Institute of Organic Chemistry used the benziodoxole reagents 2 and 3 to convert the activated oxime 1 to the alkyne 4 (Org. Lett. 2022, 24,…
Kwihwan Park, Tsuyoshi Yamada, and Hironao Sajiki of Gifu Pharmaceutical University devised conditions for the exchange of the allylic alcohol 1 with D2O, to give the trideuterated allylic alcohol 2…
Burkhard König of University Regensburg observed significant diastereoselectivity in the conversion of the ketone 1 to the aldehyde 2 (Angew. Chem. Int. PMID:30125989 Ed. 2022, 61, e202211578. DOI: 10.1002/anie.202211578). John…
Acyclic stereoarrays are important both in themselves and as precursors to enantiomerically-defined ring systems. Although the aldol condensation has for many years been a workhorse for acyclic stereoselection, there are…
6,11-Epoxyisodaucane (3) was isolated from the liverwort Tritomaria polita. In the course of the synthesis of 3, a key step of which was the decyanative cyclization of the epoxide 1…
Rong-Jie Chein of the Academia Sinica, Taipei used the known (S)-(thiolan-2-yl) diphenylmethanol benzyl ether to catalyze the Johnson-Corey-Chaykovsky cyclopropanation of the enone 1 with the allylic bromide 2 to give…
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