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C-O Ring Construction: Triciadolide C (Wang), Nesteretal A (Ito), Toxicodenane (Han), Dehydro-exo-Brevicomin (Kanomata), Diocollettines A (Houk/Smith), Heliannuol K (Green)

Chemexpress March 22, 2024 0 Comments

The maleic anhydride derivative triciadolide C (3) was isolated from the aquatic hyphomycete Tricladium castaneicola. PMID:23460641 Shaozhong Wang of Nanjing University developed a general route to such anhydrides, exemplified by…

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Organocatalyzed C-C Ring Construction: The Sattely Synthesis of Momilactone

Chemexpress March 22, 2024 0 Comments

Arnaud Voituriez of the Université Paris-Saclay used a cyclic phosphine to mediate the assembly of the cyclobutene 3 by the addition of the β-diketone 1 to the acetylene dicarboxylate 2…

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C-N Ring Construction: The Karimov Synthesis of a Nuphar Alkaloid

Chemexpress March 22, 2024 0 Comments

Weidi Cao and Xiaoming Feng of Sichuan University achieved high enantioselectivity in the ring expansion of the racemic aziridine with the isonitrile 2 to give the azetidine 3 (Org. Lett.…

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Functional Group Protection: The Murai/Arisawa Synthesis of Ansellone A

Chemexpress March 22, 2024 0 Comments

John C. Jewett of the University of Arizona demonstrated that the protected diazonium salt 1 participated efficiently in Suzuki coupling, leading the biphenyl 2 (Org. Lett. 2021, 23, 1851. DOI:…

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Post. This study confirmed the protective effect of butorphanol postC on

Chemexpress March 21, 2024 0 Comments

Post. This study confirmed the protective impact of butorphanol postC on ischaemic myocardium in reperfusion injury. We used 50 g kg1 of butorphanol primarily based on our earlier report that…

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The cells had been transfected with TRPC3 siRNA as described above and

Chemexpress March 21, 2024 0 Comments

The cells have been transfected with TRPC3 siRNA as described above and starved overnight before incubation with FSH for an added 48 hr. Cisplatin was added at a final concentration…

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Enantioselective Synthesis of Alcohols and Amines: The Yang Synthesis of Colchicine

Chemexpress March 21, 2024 0 Comments

Guosheng Liu of the Shanghai Institute of Organic Chemistry devised the enantioselective Pd-catalyzed diacetoxylation of the alkene 1 to the bis-acetate 2 (Nature Catal. 2021, 4, 172. DOI: 10.1038/s41929-021-00574-5). Bingxian…

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Substituted Benzenes: The Yang/Zhang Synthesis of Cephanolide B

Chemexpress March 21, 2024 0 Comments

Duen-Ren Hou of the National Central University devised a simple protocol for the direct acetoxylation of the substituted benzene 1, leading to the aryl acetate 2 (Org. Lett. 2021, 23,…

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Diastereoselective and Enantioselective Construction of Cyclic Ethers

Chemexpress March 21, 2024 0 Comments

Because the stereocontrolled construction of cyclic ethers has been difficult and expensive, the use of cyclic ethers as pharmaceuticals has not been fully explored. 1,2,3,4-Tetrahydrobenzoquinoline Chemical name With the development…

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Oxidation: The Cossy/Amara Route to Artemisinin

Chemexpress March 21, 2024 0 Comments

Chen Xu of the Southern University of Science and Technology and Zheng Huang of the Shanghai Institute of Organic Chemistry effected the acceptorless photochemical dehydrogenation of the sulfide 1 to…

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  • D by scaling is closer to the observed rate at 10 C
  • C experiments to mimic diagenesis at burial temperature. The outcomes highlighted
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  • 48 decrease than those perfused with BAY 412272 alone (11.15 0.91 vs. 17.76 1.87 fmol/mg tissue
  • Table 1, entry 4; Table 2, entry 1). Inside the presence of catalase (Table 2, entry

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D by scaling is closer to the observed rate at 10 C

Uncategorized

C experiments to mimic diagenesis at burial temperature. The outcomes highlighted

Uncategorized

Hed an in vitro assay in which intestinal epithelial cells were

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48 decrease than those perfused with BAY 412272 alone (11.15 0.91 vs. 17.76 1.87 fmol/mg tissue

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