Christopher Uyeda of Purdue University reduced 1 to the intermediate vinylidene (also termed "alkylidene") carbene, that cyclized to the furan 2 (ACS Catal. 2021, 11, 193. DOI: 10.1021/acscatal.0c04713). Xinhao Zhang…
Xiaobei Chen,Yanwei Hu and Shilei Zhang of Soochow University showed that the inexpensive calcium hydride could be used to reduce the aryl halide 1 to the arene 2 (Org. Chem.…
Sinupol (3), isolated from the soft coral Sinularia polydactyla, showed moderate inhibitory activity toward protein tyrosine phosphatase 1B. Koichiro Ota and Hiroaki Miyaoka of the Tokyo University of Pharmacy and…
Carbon-carbon bond formation is fundamental to all of organic chemistry. PMID:28440459 The emphasis this week is on recently-developed useful transformations that are easily scalable. Notably, these transformations telescope two or…
Bruce H. Lipshutz of the University of California, Santa Barbara developed surfactants that allowed the aqueous enzymatic reduction of the enone 1 to the ketone 2 (Chem. Commun. 2021, 57,…
Rom 3 distinct donors. (, p 0.05; , p 0.01).ing resulted in a substantial enhance in STAT1 protein levels in these cells (Fig. 3F). Paralleling STAT1 protein levels, levels of…
Bbreviated as (CP/C), revealed the differential expression of 329 genes amongst the two biofilms (see Tables two, S4 and S5). Comparison of gene expression upon selfcolonization (CC/C experiment) and upon…
Impatien A (3) was isolated from the Corydalis impatien, a flower of south China that is an important component in traditional Chinese medicine. Cyclopropanecarbaldehyde Order Donald A. Watson of the…
Marie-Isabelle Lannou and Geoffroy Sorin of the Université de Paris used Ag2O to cyclize the alkyne 1 to the furan 2 (Chem. Commun. 2022, 58, 1374. DOI: 10.1039/D1CC06379K). Rishikesh Narayan…
The sap from the elephant tree of northern Mexico, Bursera microphylla, was used locally as a cure-all for diseases, particularly those affecting the skin. Hiroshi Tanaka of the Tokyo University…
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